Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation
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منابع مشابه
Ocular drug delivery nanowafer with enhanced therapeutic efficacy.
Presently, eye injuries are treated by topical eye drop therapy. Because of the ocular surface barriers, topical eye drops must be applied several times in a day, causing side effects such as glaucoma, cataract, and poor patient compliance. This article presents the development of a nanowafer drug delivery system in which the polymer and the drug work synergistically to elicit an enhanced thera...
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15 صفحه اولStable NaCl Tolerance of Tobacco Cells Is Associated with Enhanced Accumulation of Osmotin.
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Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamellar liposomal vesicle (cMLV) formulation with a tumor-penetrating peptide, iRGD....
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Introduction: Sudden sensorineural hearing-loss (SSNHL) patients constitute approximately 2–3% of referrals to ear, nose and throat (ENT) clinics. Several predisposing factors have been proposed for this condition; one of which is vascular disorders and perfusion compromise. In this research the atherosclerotic changes and their known risk factors are studied in SSNHL patients. Materials and ...
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2011
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2011.07.023